Hydrochlorothiazide

Studies have shown a dose-dependent increased risk of non-melanoma skin cancer with exposure to increasing cumulative doses of Hydrochlorothiazide (contained in some combination products used for high blood pressure).

Patients taking Hydrochlorothiazide should:

– Regularly check for and report any new or changed skin lesions or moles
– Limit their exposure to sunlight and UV rays and use adequate protection when exposed to sunlight and UV rays to minimise the risk of skin cancer
– Make an appointment to discuss alternative options to the use of hydrochlorothiazide if you would like to and particularly if you have had a previous skin cancer.

Further information can be found on the Gov.uk website.

Date published: 11th July, 2024
Date last updated: 23rd July, 2025